Therapeutic Hypothermia for Hypoxic-Ischemic Encephalopathy in Newborn Infants
نویسندگان
چکیده
منابع مشابه
Therapeutic hypothermia for hypoxic-ischaemic encephalopathy in the newborn infant.
PURPOSE OF REVIEW This review examines recent findings from experimental models and clinical trials of induced hypothermia as treatment after cerebral hypoxia-ischaemia in term newborn infants. RECENT FINDINGS Experimental hypothermia inhibits many steps in the biochemical cascade that produces severe brain injury after hypoxia-ischaemia. This is in contrast to pharmacological agents, which t...
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OBJECTIVE To determine the risk factors for hypoxic-ischemic encephalopathy (HIE) in asphyxiated newborn infants. MATERIAL AND METHOD A retrospective study of 17,706 newborns, who were admitted to the Neonatal Unit of King Chulalongkorn Memorial Hospital, from July 1999 till the end of December 2000. 84 infants with perinatal asphyxia were enrolled in the present study. All of the possible ri...
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Objective: Several clinical trials evaluating the efficacy of hypothermia in neonates with encephalopathy have shown significant reduction in death and disability at 18-month follow-up. We sought to: 1) evaluate how the use of hypothermia for neonatal hypoxic ischemic encephalopathy (HIE) is changing in U.S. clinical practice, 2) determine which methods and devices for delivering hypothermia ar...
متن کاملNeonatal seizures and therapeutic hypothermia for hypoxic-ischemic encephalopathy.
Neonatal seizures are associated with morbidity and mortality. Hypoxic-ischemic encephalopathy (HIE) is the most common cause of seizures in newborns. Neonatal animal models suggest that therapeutic hypothermia can reduce seizures and epileptiform activity in the setting of hypoxia-ischemia, however data from human studies have conflicting results. In this research highlight, we will discuss th...
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ژورنال
عنوان ژورنال: Neonatal Medicine
سال: 2017
ISSN: 2287-9412,2287-9803
DOI: 10.5385/nm.2017.24.4.145